Hope Stansfield

Graduate Student

Hope Stansfield

Ph.D., Department of Biochemistry and Biophysics, Rensselaer Polytechnic Institute, 2008-2011.
Thesis, “Analysis of Induced Differentiation of Pulripotent Cells” November 2011.
Current Position: Post-doctoral trainee, University of Rochester Medical Center, Department of Orthopaedics, Center of Musculoskeletal Research, Rochester, NY.

Education

Ph.D., Rensselaer Polytechnic Institute, 2011 [expected]; Biochemistry and Biophysics
B.A., Smith College, 2007: Biochemistry

Research

My work here focused on analyzing human embryonic stem cells (hESC) and a cancerous analog of hESC, teratocarcinomas. Before, during, and after inducing these cells to differentiate, I analyzed the cells' physiology (morphology and growth rate), protein expression levels and localization, mRNA message level, and glycosaminoglycan (GAG) content and composition.

Publications:
1. Stansfield, Hope E., Kulczewski, Bethany P., Lybrand, Kyle E., and Jamieson, Elizabeth R. “Identifying protein interactions with metal-modified DNA using microarray technology.” Journal of Biological Inorganic Chemistry. 14:193-199, 2009.
2. Li, Boyangzi, Zhang, Zhenqing, Liu, Haiying, Stansfield, Hope E., Dordick, Jonathan S., and Linhardt, Robert J. “Analysis of Glycosaminoglycans in Stem Cell Glycomics.” in Embryonic Stem Cell Therapy for Osteodegererative Diseases. Nicole zur Neiden, Ed. Humana Press, Methods in Molecular Biology 690: 285-300, 2011.
3. Stansfield, Hope E., Gasimli, Leyla, Nairn, Alison V., Li, Boyangzi, Liu, Haiying, Paluh, Janet L., Yang, Bo, Saunders, Melanie J., Dordick, Jonathan S.; Moremen, Kelley W., and Linhardt, Robert J. “Analysis of the Structural Remodeling of Glycosaminoglycans upon Retinoic Acid-Induced Differentiation of NCCIT Cells.” Glycobiology. Submitted.

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